Lung cancer among women

Authors

  • Enriqueta Felip Hospital Universitari Vall d’Hebron

DOI:

https://doi.org/10.3989/arbor.2015.773n3005

Keywords:

adenocarcinoma, EGFR, tobacco

Abstract


Lung cancer is the most frequent malignant disease in the world. Over the last ten years lung cancer mortality has risen in Spain by 20% among women compared with 5% among men. This is due to recent changes in both genders’ smoking habits. Tobacco is still the single most important cause of a preventable disease in a high percentage of cases. It is extremely important that the population is aware of this and that people modify their lifestyle accordingly, giving up smoking in order to halt the lung cancer epidemic. In this article, we review epidemiological aspects, as well as risk factors, characteristics and the prognosis for women with lung cancer, focusing particularly on the Spanish population.

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References

Dogan, S., Shen, R., Ang, D. C., Johnson, M. L., D'Angelo, S. P., Paik, P. K., et al. (2012). Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers. Clinical Cancer Research, 18, 22, pp. 6169-6177. http://dx.doi.org/10.1158/1078-0432.CCR-11-3265

Ferlay, J., Steliarova-Foucher, E., Lortet-Tieulent, J., Rosso, S., Coebergh, J. W., Comber, H., et al. (2013). Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. European Journal of Cancer, 49, 6, pp. 1374-1403. http://dx.doi.org/10.1016/j.ejca.2012.12.027

Fernández, E., Schiaffino, A., Borras, J. M., Shafey, O., Villalbi, J. R. y La Vecchia, C. (2003). Prevalence of cigarette smoking by birth cohort among males and females in Spain, 1910-1990. European Journal of Cancer Prevention, 12, 1, pp. 57-62. http://dx.doi.org/10.1097/00008469-200302000-00009

Freedman, N. D., Leitzmann, M. F., Hollenbeck, A. R., Schatzkin, A. y Abnet, C. C. (2008). Cigarette smoking and subsequent risk of lung cancer in men and women: analysis of a prospective cohort study. Lancet Oncology, 9, 7, pp. 649-656. http://dx.doi.org/10.1016/S1470-2045(08)70154-2

Fu, J. B., Kau, T. Y., Severson, R. K. y Kalemkerian, G. P. (2005). Lung cancer in women: analysis of the national Surveillance, Epidemiology, and End Results database. Chest, 127, 3, pp. 768-777. http://dx.doi.org/10.1378/chest.127.3.768

Henschke, C. I., Yip, R. y Miettinen, O. S. (2006). Women's susceptibility to tobacco carcinogens and survival after diagnosis of lung cancer. Journal of the American Association, 296, 2, pp. 180-184. DOI: 296/2/180 [pii]10.1001/jama.296.2.180.

Hsu, L. H., Chu, N. M., Liu, C. C., Tsai, S. Y., You, D. L., Ko, J. S., et al. (2009). Sex-associated differences in non-small cell lung cancer in the new era: is gender an independent prognostic factor? Lung Cancer, 66, 2, pp. 262-267.

Isla, D., Felip, E., Garrido, P., Vinolas, N., Garcia-Campelo, R., Lianes, P., et al. (2007). Sex differences in non-small cell lung cancer (NSCLC) patients (p) participating in Spanish Lung Cancer Group (SLCG) trials. ASCO Meeting Abstracts, 25, 18_suppl, pp. 7679.

Isla, D., Provencio, M., Majem, M., Felip, E., Vinolas, N., Campelo, R. G., et al. (2012). Never-smoking women with lung cancer from the Spanish WORLD07 database. ASCO Meeting Abstracts, 30, 15_suppl, pp. 1531.

Janjigian, Y. Y., McDonnell, K., Kris, M. G., Shen, R., Sima, C. S., Bach, P. B., et al. (2010). Pack-years of cigarette smoking as a prognostic factor in patients with stage IIIB/IV nonsmall cell lung cancer. Cancer, 116, 3, pp. 670-675. http://dx.doi.org/10.1002/cncr.24813

Khuder, S. A. (2001). Effect of cigarette smoking on major histological types of lung cancer: a meta-analysis. Lung Cancer, 31, 2-3, pp. 139-148. http://dx.doi.org/10.1016/S0169-5002(00)00181-1

Li, Q., Dresler, C., Heck, J. E., Allwright, S., Haglund, M., Sanchez, S., et al. (2010). Knowledge and beliefs about smoking and cancer among women in five European countries. Cancer Epidemiology, Biomarkers and Prevention, 19, 11, pp. 2811-2820. http://dx.doi.org/10.1158/1055-9965.EPI-10-0432

Lortet-Tieulent, J., Soerjomataram, I., Ferlay, J., Rutherford, M., Weiderpass, E. y Bray, F. (2014). International trends in lung cancer incidence by histological subtype: adenocarcinoma stabilizing in men but still increasing in women. Lung Cancer, 84, 1, pp. 13-22. http://dx.doi.org/10.1016/j.lungcan.2014.01.009

Majem, M., Artal, A., De Castro, J., Felip, E., Garrido Lopez, P., Isla, D., et al. (2012). Population survey to assess the knowledge of smoking habit and its consequences on women (w) in Spain. ASCO Meeting Abstracts, 30, 15_suppl, pp. e12000.

Malvezzi, M., Bertuccio, P., Levi, F., La Vecchia, C. y Negri, E. (2014). European cancer mortality predictions for the year 2014. Annals of Oncology, 25, 8, pp. 1650-1656. http://dx.doi.org/10.1093/annonc/mdu138

Marchetti, A., Felicioni, L., Malatesta, S., Grazia Sciarrotta, M., Guetti, L., Chella, A., et al. (2011). Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. Journal of Clinical Oncology, 29, 26, pp. 3574-3579. http://dx.doi.org/10.1200/JCO.2011.35.9638

Martínez-Sánchez, J. M., Fernández, E., Fu, M., Gallus, S., Martínez, C., Sureda, X., et al. (2010). Smoking behaviour, involuntary smoking, attitudes towards smoke-free legislations, and tobacco control activities in the European Union. PLoS One, 5, 11, pp. e13881. http://dx.doi.org/10.1371/journal.pone.0013881

Mazieres, J., Peters, S., Lepage, B., Cortot, A. B., Barlesi, F., Beau-Faller, M., et al. (2013a). Lung cancer that harbors an HER2 mutation: epidemiologic characteristics and therapeutic perspectives. Journal of Clinical Oncology, 31, 16, pp. 1997-2003.

Mazieres, J., Rouquette, I., Lepage, B., Milia, J., Brouchet, L., Guibert, N., et al. (2013b). Specificities of lung adenocarcinoma in women who have never smoked. Journal of Thoracic Oncology, 8, 7, pp. 923-929.

Micheli, A., Ciampichini, R., Oberaigner, W., Ciccolallo, L., de Vries, E., Izarzugaza, I., et al. (2009). The advantage of women in cancer survival: an analysis of EUROCARE-4 data. European Journal of Cancer, 45, 6, pp. 1017-1027. http://dx.doi.org/10.1016/j.ejca.2008.11.008

Nakamura, H., Ando, K., Shinmyo, T., Morita, K., Mochizuki, A., Kurimoto, N., et al. (2011). Female gender is an independent prognostic factor in non-small-cell lung cancer: a meta-analysis. Annals f Thoracic and Cardiovascular Surgery, 17, 5, pp. 469-480. http://dx.doi.org/10.5761/atcs.oa.10.01637

Ng, M., Freeman, M. K., Fleming, T. D., Robinson, M., Dwyer-Lindgren, L., Thomson, B., et al. (2014). Smoking prevalence and cigarette consumption in 187 countries, 1980-2012. Journal of the American Association, 311, 2, pp. 183-192. http://dx.doi.org/10.1001/jama.2013.284692

Paik, P. K., Johnson, M. L., D'Angelo, S. P., Sima, C. S., Ang, D., Dogan, S., et al. (2012). Driver mutations determine survival in smokers and never-smokers with stage IIIB/IV lung adenocarcinomas. Cancer, 118, 23, pp. 5840-5847. http://dx.doi.org/10.1002/cncr.27637

Papadopoulous, A., Guida, F. y Leffondré, K. (2014). Heavy smoking and lung cancer: are women at high risk? Results of ICARE study. British Journal of Cancer, 110, pp. 1358-1391. http://dx.doi.org/10.1038/bjc.2013.821

Radzikowska, E., Glaz, P. y Roszkowski, K. (2002). Lung cancer in women: age, smoking, histology, performance status, stage, initial treatment and survival. Population-based study of 20 561 cases. Annals of Oncology, 13, 7, pp. 1087-1093.

Ries, L., Young, J., Keel, G., Eisner, M., Lin, Y. y Horner, M. e. (2007). SEER survival monograph: Cancer survival among adults: US SEER program, 1988-2001: patient and tumor characteristics. NIH publications no 07-6215. Bethesda, MD: National Cancer Institute [en línea]. [Fecha de consulta: julio 2013]. Disponible en: http://seer.cancer.gov/publications/survival/

Rouquette, I., Lauwers-Cances, V., Allera, C., Brouchet, L., Milia, J., Nicaise, Y., et al. (2012). Characteristics of lung cancer in women: importance of hormonal and growth factors. Lung Cancer, 76, 3, pp. 280-285. http://dx.doi.org/10.1016/j.lungcan.2011.11.023

Sagerup, C. M., Smastuen, M. y Johannesen, T. B. (2001). Sex-specific trends in lung cancer incidence and survival: a population study of 40.118 cases. Thorax, 66, pp. 301-307. http://dx.doi.org/10.1136/thx.2010.151621

Salmeron, D., Chirlaque, M. D., Isabel Izarzugaza, M., Sanchez, M. J., Marcos-Gragera, R., Ardanaz, E., et al. (2012). Lung cancer prognosis in Spain: the role of histology, age and sex. Respiratory Medicine, 106, 9, pp. 1301-1308. http://dx.doi.org/10.1016/j.rmed.2012.06.006

Sánchez, M. J., Payer, T., De Angelis, R., Larranaga, N., Capocaccia, R. y Martínez, C. (2010). Cancer incidence and mortality in Spain: estimates and projections for the period 1981-2012. Annals of Oncology, 21, Suppl 3, pp. iii30-36. DOI: mdq090 [pii]10.1093/annonc/mdq090.

Steliarova-Foucher, E., O'Callaghan, M. y Ferlay, J. (2012). European Cancer Observatory: cancer incidence, mortality, prevalence and survival in Europe. Version 1.0. European Network of Cancer Registries, International Agency for Research on Cancer [en línea]. [Fecha de consulta: febrero 2913]. Disponible en: http://eco.iarc.fr.

Torre, L. A., Siegel, R. L., Ward, E. M. y Jemal, A. (2014). International variation in lung cancer mortality rates and trends among women. Cancer Epidemiology, Biomarkers and Prevention, 23, 6, pp. 1025-1036. http://dx.doi.org/10.1158/1055-9965.EPI-13-1220

Wakelee, H. A., Dahlberg, S. E., Brahmer, J. R., Schiller, J. H., Perry, M. C., Langer, C. J., et al. (2012). Differential effect of age on survival in advanced NSCLC in women versus men: analysis of recent Eastern Cooperative Oncology Group (ECOG) studies, with and without bevacizumab. Lung Cancer, 76, 3, pp. 410-415. http://dx.doi.org/10.1016/j.lungcan.2011.12.006

Wheatley-Price, P., Blackhall, F., Lee, S. M., Ma, C., Ashcroft, L., Jitlal, M., et al. (2010). The influence of sex and histology on outcomes in non-small-cell lung cancer: a pooled analysis of five randomized trials. Annals of Oncology, 21, 10, pp. 2023-2028. http://dx.doi.org/10.1093/annonc/mdq067

Zang, E. A. y Wynder, E. L. (1996). Differences in lung cancer risk between men and women: examination of the evidence. Journal of the National Cancer Institute, 88, 3-4, pp. 183-192. http://dx.doi.org/10.1093/jnci/88.3-4.183

Published

2015-06-30

How to Cite

Felip, E. (2015). Lung cancer among women. Arbor, 191(773), a235. https://doi.org/10.3989/arbor.2015.773n3005

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Articles