Generación rayos X – mayoría de edad

Gavin Connor Fox

doi:10.3989/arbor.2015.772n2007

Autores/as

Gavin Connor Fox Synchrotron Soleil

DOI:

https://doi.org/10.3989/arbor.2015.772n2007

Palabras clave:

biología estructural, cristalografía de proteínas, cristalografía en serie, línea, fuentes de luz, microfluídica, proteínas de membrana, sincrotrón, XFEL

Resumen

La comunidad científica celebró en 2014 el impacto que la cristalografía ha tenido sobre la ciencia fundamental y aplicada, así como los de descubrimientos relevantes que nos han proporcionado una visión del mundo a escala molecular y nanométrica. La UNESCO ha declarado 2015 como el Año Internacional de la Luz por lo que quizás es un buen momento para reflexionar sobre el papel que han jugado y juegan los sincrotrones en esta ciencia. El acceso a la radiación sincrotrón ha revolucionado nuestra capacidad para explorar las propiedades, interacciones y estructura de materiales, así como ampliado nuestro conocimiento en distintos contextos científicos, desde el patrimonio cultural a la nanotecnología y nuevos materiales, hasta la exploración de sistemas celulares y búsqueda de fármacos. El rango de potenciales aplicaciones de los sincrotrones y sus campos de interés es vasto y queda fuera del alcance de un único artículo por lo que la intención del autor es la de proporcionar una imagen de los sincrotrones obtenida a través del filtro de la cristalografía macromolecular. Echaremos la vista atrás para ver cómo los sincrotrones han ido evolucionado hasta llegar a las actuales instalaciones en donde las líneas de trabajo asociadas a los mismos se están adaptado rápidamente a la introducción de las técnicas de alto rendimiento en el cambio del milenio; pero también miraremos hacia el futuro, hacia las nuevas tendencias y tecnologías que ya están transformando las actuales instalaciones y la misma cristalografía.

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Citas

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