Proteómica y biología de sistemas para el estudio de la alergia alimentaria
DOI:
https://doi.org/10.3989/arbor.2020.795n1010Palabras clave:
roteómica, biología de sistemas, alimentos, alergiaResumen
La alergia alimentaria es el cuarto principal problema de salud pública según datos de la Organización Mundial de la Salud (OMS). Afecta a un total de 6-8% de niños y a 2-4% de adultos. Debido a la actual gran prevalencia de la alergia alimentaria, se hace necesario el desarrollo de nuevos métodos de control, tratamiento y estudio. En esta revisión se presentan los enfoques proteómicos y de biología de sistemas más recientes para el estudio de la alergia alimentaria. En este sentido, se resumen con detalle las dos principales estrategias proteómicas (proteómica de descubrimiento y proteómica dirigida). También se describen los innovadores enfoques de biología de sistemas basados en datos proteómicos para el estudio de los mecanismos de la alergia alimentaria. Finalmente se presentan nuevas perspectivas y futuras direcciones.
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